| Regular Season: Week 1 |
 Seahawks |
at |
 Rams |
Sunday, September 13, 2015 |
1:00PM |
SEA 31, STL 34 |
| Regular Season: Week 2 |
Rams |
at |
 Redskins |
Sunday, September 20, 2015 |
1:00PM |
STL 10, WAS 24 |
| Regular Season: Week 3 |
 Steelers |
at |
Rams |
Sunday, September 27, 2015 |
1:00PM |
PIT 12, STL 6 |
| Regular Season: Week 4 |
Rams |
at |
 Cardinals |
Sunday, October 4, 2015 |
4:25PM |
STL 24, ARI 22 |
| Regular Season: Week 5 |
Rams |
at |
 Packers |
Sunday, October 11, 2015 |
1:00PM |
STL 10, GB 24 |
| Regular Season: Week 7 |
 Browns |
at |
Rams |
Sunday, October 25, 2015 |
1:00PM |
CLE 6, STL 24 |
| Regular Season: Week 8 |
 49ers |
at |
Rams |
Sunday, November 1, 2015 |
1:00PM |
SF 6, STL 27 |
| Regular Season: Week 9 |
Rams |
at |
 Vikings |
Sunday, November 8, 2015 |
1:00PM |
STL 18, MIN 21 |
| Regular Season: Week 10 |
 Bears |
at |
Rams |
Sunday, November 15, 2015 |
1:00PM |
CHI 37, STL 13 |
| Regular Season: Week 11 |
Rams |
at |
 Ravens |
Sunday, November 22, 2015 |
1:00PM |
STL 13, BAL 16 |
| Regular Season: Week 12 |
Rams |
at |
 Bengals |
Sunday, November 29, 2015 |
1:00PM |
STL 7, CIN 31 |
| Regular Season: Week 13 |
Cardinals |
at |
Rams |
Sunday, December 6, 2015 |
1:00PM |
ARI 27, STL 3 |
| Regular Season: Week 14 |
 Lions |
at |
Rams |
Sunday, December 13, 2015 |
1:00PM |
DET 14, STL 21 |
| Regular Season: Week 15 |
 Buccaneers |
at |
Rams |
Thursday, December 17, 2015 |
8:25PM |
TB 23, STL 31 |
| Regular Season: Week 16 |
Rams |
at |
Seahawks |
Sunday, December 27, 2015 |
4:25PM |
STL 23, SEA 17 |
| Regular Season: Week 17 |
Rams |
at |
49ers |
Sunday, January 3, 2016 |
4:25PM |
STL 16, SF 19 |