| Regular Season: Week 1 |
 Texans |
at |
 Chiefs |
Thursday, September 10, 2020 |
8:20PM |
HOU 20, KC 34 |
| Regular Season: Week 2 |
 Ravens |
at |
Texans |
Sunday, September 20, 2020 |
4:25PM |
BAL 33, HOU 16 |
| Regular Season: Week 3 |
Texans |
at |
 Steelers |
Sunday, September 27, 2020 |
1:00PM |
HOU 21, PIT 28 |
| Regular Season: Week 4 |
 Vikings |
at |
Texans |
Sunday, October 4, 2020 |
1:00PM |
MIN 31, HOU 23 |
| Regular Season: Week 5 |
 Jaguars |
at |
Texans |
Sunday, October 11, 2020 |
1:00PM |
JAX 14, HOU 30 |
| Regular Season: Week 6 |
Texans |
at |
 Titans |
Sunday, October 18, 2020 |
1:00PM |
HOU 36, TEN 42 |
| Regular Season: Week 7 |
 Packers |
at |
Texans |
Sunday, October 25, 2020 |
1:00PM |
GB 35, HOU 20 |
| Regular Season: Week 9 |
Texans |
at |
Jaguars |
Sunday, November 8, 2020 |
1:00PM |
HOU 27, JAX 25 |
| Regular Season: Week 10 |
Texans |
at |
 Browns |
Sunday, November 15, 2020 |
1:00PM |
HOU 7, CLE 10 |
| Regular Season: Week 11 |
 Patriots |
at |
Texans |
Sunday, November 22, 2020 |
1:00PM |
NE 20, HOU 27 |
| Regular Season: Week 12 |
Texans |
at |
 Lions |
Thursday, November 26, 2020 |
12:30PM |
HOU 41, DET 25 |
| Regular Season: Week 13 |
 Colts |
at |
Texans |
Sunday, December 6, 2020 |
1:00PM |
IND 26, HOU 20 |
| Regular Season: Week 14 |
Texans |
at |
 Bears |
Sunday, December 13, 2020 |
1:00PM |
HOU 7, CHI 36 |
| Regular Season: Week 15 |
Texans |
at |
Colts |
Sunday, December 20, 2020 |
1:00PM |
HOU 20, IND 27 |
| Regular Season: Week 16 |
 Bengals |
at |
Texans |
Sunday, December 27, 2020 |
1:00PM |
CIN 37, HOU 31 |
| Regular Season: Week 17 |
Titans |
at |
Texans |
Sunday, January 3, 2021 |
4:25PM |
TEN 41, HOU 38 |