| Regular Season: Week 1 |
 Titans |
at |
 Bills |
Sunday, September 3, 2000 |
8:20PM |
TEN 13, BUF 16 |
| Regular Season: Week 2 |
 Chiefs |
at |
Titans |
Sunday, September 10, 2000 |
1:00PM |
KC 14, TEN 17 |
| Regular Season: Week 4 |
Titans |
at |
 Steelers |
Sunday, September 24, 2000 |
1:00PM |
TEN 23, PIT 20 |
| Regular Season: Week 5 |
 Giants |
at |
Titans |
Sunday, October 1, 2000 |
1:00PM |
NYG 14, TEN 28 |
| Regular Season: Week 6 |
Titans |
at |
 Bengals |
Sunday, October 8, 2000 |
1:00PM |
TEN 23, CIN 14 |
| Regular Season: Week 7 |
 Jaguars |
at |
Titans |
Monday, October 16, 2000 |
9:00PM |
JAC 13, TEN 27 |
| Regular Season: Week 8 |
Titans |
at |
 Ravens |
Sunday, October 22, 2000 |
1:00PM |
TEN 14, BAL 6 |
| Regular Season: Week 9 |
Titans |
at |
 Redskins |
Monday, October 30, 2000 |
9:00PM |
TEN 27, WAS 21 |
| Regular Season: Week 10 |
Steelers |
at |
Titans |
Sunday, November 5, 2000 |
1:00PM |
PIT 7, TEN 9 |
| Regular Season: Week 11 |
Ravens |
at |
Titans |
Sunday, November 12, 2000 |
1:00PM |
BAL 24, TEN 23 |
| Regular Season: Week 12 |
 Browns |
at |
Titans |
Sunday, November 19, 2000 |
1:00PM |
CLE 10, TEN 24 |
| Regular Season: Week 13 |
Titans |
at |
Jaguars |
Sunday, November 26, 2000 |
4:15PM |
TEN 13, JAC 16 |
| Regular Season: Week 14 |
Titans |
at |
 Eagles |
Sunday, December 3, 2000 |
1:00PM |
TEN 15, PHI 13 |
| Regular Season: Week 15 |
Bengals |
at |
Titans |
Sunday, December 10, 2000 |
1:00PM |
CIN 3, TEN 35 |
| Regular Season: Week 16 |
Titans |
at |
Browns |
Sunday, December 17, 2000 |
1:00PM |
TEN 24, CLE 0 |
| Regular Season: Week 17 |
 Cowboys |
at |
Titans |
Monday, December 25, 2000 |
9:00PM |
DAL 0, TEN 31 |
| Divisional Playoffs: Week 19 |
Ravens |
at |
Titans |
Sunday, January 7, 2001 |
12:30PM |
BAL 24, TEN 10 |