| Regular Season: Week 1 |
 Titans |
at |
 Dolphins |
Sunday, September 9, 2018 |
1:00PM |
TEN 20, MIA 27 |
| Regular Season: Week 2 |
 Texans |
at |
Titans |
Sunday, September 16, 2018 |
1:00PM |
HOU 17, TEN 20 |
| Regular Season: Week 3 |
Titans |
at |
 Jaguars |
Sunday, September 23, 2018 |
1:00PM |
TEN 9, JAX 6 |
| Regular Season: Week 4 |
 Eagles |
at |
Titans |
Sunday, September 30, 2018 |
1:00PM |
PHI 23, TEN 26 |
| Regular Season: Week 5 |
Titans |
at |
 Bills |
Sunday, October 7, 2018 |
1:00PM |
TEN 12, BUF 13 |
| Regular Season: Week 6 |
 Ravens |
at |
Titans |
Sunday, October 14, 2018 |
4:25PM |
BAL 21, TEN 0 |
| Regular Season: Week 7 |
Titans |
at |
 Chargers |
Sunday, October 21, 2018 |
9:30PM |
TEN 19, LAC 20 |
| Regular Season: Week 9 |
Titans |
at |
 Cowboys |
Monday, November 5, 2018 |
8:15PM |
TEN 28, DAL 14 |
| Regular Season: Week 10 |
 Patriots |
at |
Titans |
Sunday, November 11, 2018 |
1:00PM |
NE 10, TEN 34 |
| Regular Season: Week 11 |
Titans |
at |
 Colts |
Sunday, November 18, 2018 |
1:00PM |
TEN 10, IND 38 |
| Regular Season: Week 12 |
Titans |
at |
Texans |
Monday, November 26, 2018 |
8:15PM |
TEN 17, HOU 34 |
| Regular Season: Week 13 |
 Jets |
at |
Titans |
Sunday, December 2, 2018 |
4:05PM |
NYJ 22, TEN 26 |
| Regular Season: Week 14 |
Jaguars |
at |
Titans |
Thursday, December 6, 2018 |
8:20PM |
JAX 9, TEN 30 |
| Regular Season: Week 15 |
Titans |
at |
 Giants |
Sunday, December 16, 2018 |
1:00PM |
TEN 17, NYG 0 |
| Regular Season: Week 16 |
 Redskins |
at |
Titans |
Saturday, December 22, 2018 |
4:30PM |
WAS 16, TEN 25 |
| Regular Season: Week 17 |
Colts |
at |
Titans |
Sunday, December 30, 2018 |
8:20PM |
IND 33, TEN 17 |