| Regular Season: Week 1 |
 Dolphins |
at |
 Colts |
Sunday, September 6, 1998 |
3:00PM |
MIA 24, IND 15 |
| Regular Season: Week 2 |
Colts |
at |
 Patriots |
Sunday, September 13, 1998 |
3:00PM |
IND 6, NE 29 |
| Regular Season: Week 3 |
Colts |
at |
 Jets |
Sunday, September 20, 1998 |
3:00PM |
IND 6, NYJ 44 |
| Regular Season: Week 4 |
 Saints |
at |
Colts |
Sunday, September 27, 1998 |
3:00PM |
NO 19, IND 13 |
| Regular Season: Week 5 |
 Chargers |
at |
Colts |
Sunday, October 4, 1998 |
3:00PM |
SD 12, IND 17 |
| Regular Season: Week 6 |
 Bills |
at |
Colts |
Sunday, October 11, 1998 |
3:00PM |
BUF 31, IND 24 |
| Regular Season: Week 7 |
Colts |
at |
 49ers |
Sunday, October 18, 1998 |
3:00PM |
IND 31, SF 34 |
| Regular Season: Week 9 |
Patriots |
at |
Colts |
Sunday, November 1, 1998 |
3:00PM |
NE 21, IND 16 |
| Regular Season: Week 10 |
Colts |
at |
Dolphins |
Sunday, November 8, 1998 |
3:00PM |
IND 14, MIA 27 |
| Regular Season: Week 11 |
Jets |
at |
Colts |
Sunday, November 15, 1998 |
3:00PM |
NYJ 23, IND 24 |
| Regular Season: Week 12 |
Colts |
at |
Bills |
Sunday, November 22, 1998 |
3:00PM |
IND 11, BUF 34 |
| Regular Season: Week 13 |
Colts |
at |
 Ravens |
Sunday, November 29, 1998 |
3:00PM |
IND 31, BAL 38 |
| Regular Season: Week 14 |
Colts |
at |
 Falcons |
Sunday, December 6, 1998 |
3:00PM |
IND 21, ATL 28 |
| Regular Season: Week 15 |
 Bengals |
at |
Colts |
Sunday, December 13, 1998 |
3:00PM |
CIN 26, IND 39 |
| Regular Season: Week 16 |
Colts |
at |
 Seahawks |
Sunday, December 20, 1998 |
3:00PM |
IND 23, SEA 27 |
| Regular Season: Week 17 |
 Panthers |
at |
Colts |
Sunday, December 27, 1998 |
3:00PM |
CAR 27, IND 19 |